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Using Optical Tweezers to Monitor Allosteric Signals Through Changes in Folding Energy Landscapes

Using Optical Tweezers to Monitor Allosteric Signals Through Changes in Folding Energy Landscapes

Publication

Title of Publication
Using Optical Tweezers to Monitor Allosteric Signals Through Changes in Folding Energy Landscapes
Publication Year
2022
Authors
Bai L, Malmosi M, Good L, Maillard RA.
Journal
Methods Mol Biol
DOI
https://doi.org/10.1007/978-1-0716-2229-2_18

Construct

Construct Name
cyclic nucleotide binding (CNB) domain
Gene Name
PKA RIα
Sequence
RRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
PDB ID
1RGS
UniProt link
https://www.uniprot.org/uniprotkb/P00514/entry